Atherosclerosis Research Lab »  Publications

Publications

View by Year:
 
Ceron CS, Baligand C, Joshi S, Wanga S, Cowley PM, Walker JP, Song SH, Mahimkar R, Baker AJ, Raffai RL, Wang ZJ, Lovett DH
An intracellular matrix metalloproteinase-2 isoform induces tubular regulated necrosis: implications for acute kidney injury.
American journal of physiology. Renal physiology, Jun-01-2017;312(6):F1166-F1183.
Tie G, Yan J, Messina JA, Raffai RL, Messina LM
Inhibition of p38 Mitogen-Activated Protein Kinase Enhances the Apoptosis Induced by Oxidized Low-Density Lipoprotein in Endothelial Progenitor Cells.
Journal of vascular research, Apr-1-2016;[Epub ahead of print]52(6):361-371.
Luk FS, Kim RY, Li K, Ching D, Wong DK, Joshi SK, Imhof I, Honbo N, Hoover H, Zhu BQ, Lovett DH, Karliner JS, Raffai RL
Immunosuppression With FTY720 Reverses Cardiac Dysfunction in Hypomorphic ApoE Mice Deficient in SR-BI Expression That Survive Myocardial Infarction Caused by Coronary Atherosclerosis.
Journal of cardiovascular pharmacology, Jan-2016;67(1):47-56.
Cheung KH, Keerthikumar S, Roncaglia P, Subramanian SL, Roth ME, Samuel M, Anand S, Gangoda L, Gould S, Alexander R, Galas D, Gerstein MB, Hill AF, Kitchen RR, Lötvall J, Patel T, Procaccini DC, Quesenberry P, Rozowsky J, Raffai RL, Shypitsyna A, Su AI, Théry C, Vickers K, Wauben MH, Mathivanan S, Milosavljevic A, Laurent LC
Extending gene ontology in the context of extracellular RNA and vesicle communication.
Journal of biomedical semantics, 2016;[epublish]7:19.
Li K, Ching D, Luk FS, Raffai RL
Apolipoprotein E enhances microRNA-146a in monocytes and macrophages to suppress nuclear factor-κB-driven inflammation and atherosclerosis.
Circulation research, Jun-19-2015;117(1):e1-e11.  Epub 2015 Apr 22.
Mattis AN, Song G, Hitchner K, Kim RY, Lee AY, Sharma AD, Malato Y, McManus MT, Esau CC, Koller E, Koliwad S, Lim LP, Maher JJ, Raffai RL, Willenbring H
A screen in mice uncovers repression of lipoprotein lipase by microRNA-29a as a mechanism for lipid distribution away from the liver.
Hepatology (Baltimore, Md.), Jan-2015;61(1):141-52.  Epub 2014 Nov 24.
Laurent LC, Abdel-Mageed AB, Adelson PD, Arango J, Balaj L, Breakefield X, Carlson E, Carter BS, Majem B, Chen CC, Cocucci E, Danielson K, Courtright A, Das S, Abd Elmageed ZY, Enderle D, Ezrin A, Ferrer M, Freedman J, Galas D, Gandhi R, Huentelman MJ, Van Keuren-Jensen K, Kalani Y, Kim Y, Krichevsky AM, Lai C, Lal-Nag M, Laurent CD, Leonardo T, Li F, Malenica I, Mondal D, Nejad P, Patel T, Raffai RL, Rubio R, Skog J, Spetzler R, Sun J, Tanriverdi K, Vickers K, Wang L, Wang Y, Wei Z, Weiner HL, Wong D, Yan IK, Yeri A, Gould S
Meeting report: discussions and preliminary findings on extracellular RNA measurement methods from laboratories in the NIH Extracellular RNA Communication Consortium.
Journal of extracellular vesicles, 2015;[epublish]4:26533.
Patton JG, Franklin JL, Weaver AM, Vickers K, Zhang B, Coffey RJ, Ansel KM, Blelloch R, Goga A, Huang B, L'Etoille N, Raffai RL, Lai CP, Krichevsky AM, Mateescu B, Greiner VJ, Hunter C, Voinnet O, McManus MT
Biogenesis, delivery, and function of extracellular RNA.
Journal of extracellular vesicles, 2015;[epublish]4:27494.
Wang G, Kim RY, Imhof I, Honbo N, Luk FS, Li K, Kumar N, Zhu BQ, Eberlé D, Ching D, Karliner JS, Raffai RL
The immunosuppressant FTY720 prolongs survival in a mouse model of diet-induced coronary atherosclerosis and myocardial infarction.
Journal of cardiovascular pharmacology, Feb-2014;63(2):132-43.
Gaudreault N, Kumar N, Olivas VR, Eberlé D, Stephens K, Raffai RL
Hyperglycemia impairs atherosclerosis regression in mice.
The American journal of pathology, Dec-2013;183(6):1981-92.  Epub 2013 Oct 8.
Eberlé D, Luk FS, Kim RY, Olivas VR, Kumar N, Posada JM, Li K, Gaudreault N, Rapp JH, Raffai RL
Inducible ApoE gene repair in hypomorphic ApoE mice deficient in the low-density lipoprotein receptor promotes atheroma stabilization with a human-like lipoprotein profile.
Arteriosclerosis, thrombosis, and vascular biology, Aug-2013;33(8):1759-67.  Epub 2013 Jun 20.
Lovett DH, Mahimkar R, Raffai RL, Cape L, Zhu BQ, Jin ZQ, Baker AJ, Karliner JS
N-terminal truncated intracellular matrix metalloproteinase-2 induces cardiomyocyte hypertrophy, inflammation and systolic heart failure.
PloS one, 2013;[epublish]8(7):e68154.
Raffai RL
Apolipoprotein E regulation of myeloid cell plasticity in atherosclerosis.
Current opinion in lipidology, Oct-2012;23(5):471-8.
Eberlé D, Kim RY, Luk FS, de Mochel NS, Gaudreault N, Olivas VR, Kumar N, Posada JM, Birkeland AC, Rapp JH, Raffai RL
Apolipoprotein E4 domain interaction accelerates diet-induced atherosclerosis in hypomorphic Arg-61 apoe mice.
Arteriosclerosis, thrombosis, and vascular biology, May-2012;32(5):1116-23.  Epub 2012 Mar 22.
Gaudreault N, Kumar N, Posada JM, Stephens KB, Reyes de Mochel NS, Eberlé D, Olivas VR, Kim RY, Harms MJ, Johnson S, Messina LM, Rapp JH, Raffai RL
ApoE suppresses atherosclerosis by reducing lipid accumulation in circulating monocytes and the expression of inflammatory molecules on monocytes and vascular endothelium.
Arteriosclerosis, thrombosis, and vascular biology, Feb-2012;32(2):264-72.  Epub 2011 Nov 3.
Lovett DH, Mahimkar R, Raffai RL, Cape L, Maklashina E, Cecchini G, Karliner JS
A novel intracellular isoform of matrix metalloproteinase-2 induced by oxidative stress activates innate immunity.
PloS one, 2012;7(4):e34177.
Gaudreault N, Kumar N, Olivas VR, Eberlé D, Rapp JH, Raffai RL
Macrophage-specific apoE gene repair reduces diet-induced hyperlipidemia and atherosclerosis in hypomorphic Apoe mice.
PloS one, 2012;7(5):e35816.
Tao R, Hoover HE, Honbo N, Kalinowski M, Alano CC, Karliner JS, Raffai R
High-density lipoprotein determines adult mouse cardiomyocyte fate after hypoxia-reoxygenation through lipoprotein-associated sphingosine 1-phosphate.
American journal of physiology. Heart and circulatory physiology, Mar-2010;298(3):H1022-8.  Epub 2010 Jan 8.
Tie G, Yan J, Yang Y, Park BD, Messina JA, Raffai RL, Nowicki PT, Messina LM
Oxidized low-density lipoprotein induces apoptosis in endothelial progenitor cells by inactivating the phosphoinositide 3-kinase/Akt pathway.
Journal of vascular research, 2010;47(6):519-30.  Epub 2010 Apr 30.
Zhang S, Picard MH, Vasile E, Zhu Y, Raffai RL, Weisgraber KH, Krieger M
Diet-induced occlusive coronary atherosclerosis, myocardial infarction, cardiac dysfunction, and premature death in scavenger receptor class B type I-deficient, hypomorphic apolipoprotein ER61 mice.
Circulation, Jun-28-2005;111(25):3457-64.  Epub 2005 Jun 20.
Raffai RL, Loeb SM, Weisgraber KH
Apolipoprotein E promotes the regression of atherosclerosis independently of lowering plasma cholesterol levels.
Arteriosclerosis, thrombosis, and vascular biology, Feb-2005;25(2):436-41.
Raffaï RL, McPherson R, Weisgraber KH, Innerarity TL, Rassart E, Bersot TP, Milne RW
Antibody phenotyping test for the human apolipoprotein E2 isoform.
Clinical chemistry, Sep-2003;49(9):1524-6.
Raffai RL, Weisgraber KH
Cholesterol: from heart attacks to Alzheimer's disease.
Journal of lipid research, Aug-2003;44(8):1423-30.
Raffaï RL, Hasty AH, Wang Y, Mettler SE, Sanan DA, Linton MF, Fazio S, Weisgraber KH
Hepatocyte-derived ApoE is more effective than non-hepatocyte-derived ApoE in remnant lipoprotein clearance.
The Journal of biological chemistry, Mar-28-2003;278(13):11670-5.
Raffai RL, Weisgraber KH
Hypomorphic apolipoprotein E mice: a new model of conditional gene repair to examine apolipoprotein E-mediated metabolism.
The Journal of biological chemistry, Mar-29-2002;277(13):11064-8.
Raffai RL, Dong LM, Farese RV, Weisgraber KH
Introduction of human apolipoprotein E4 "domain interaction" into mouse apolipoprotein E.
Proceedings of the National Academy of Sciences of the United States of America, Sep-25-2001;98(20):11587-91.
Raffaï R, Weisgraber KH, MacKenzie R, Rupp B, Rassart E, Hirama T, Innerarity TL, Milne R
Binding of an antibody mimetic of the human low density lipoprotein receptor to apolipoprotein E is governed through electrostatic forces. Studies using site-directed mutagenesis and molecular modeling.
The Journal of biological chemistry, Mar-10-2000;275(10):7109-16.
Raffaï R, Vukmirica J, Weisgraber KH, Rassart E, Innerarity TL, Milne R
Bacterial expression and purification of the Fab fragment of a monoclonal antibody specific for the low-density lipoprotein receptor-binding site of human apolipoprotein E.
Protein expression and purification, Jun-1999;16(1):84-90.
Raffai R, Maurice R, Weisgraber K, Innerarity T, Wang X, MacKenzie R, Hirama T, Watson D, Rassart E, Milne R
Molecular characterization of two monoclonal antibodies specific for the LDL receptor-binding site of human apolipoprotein E.
Journal of lipid research, Sep-1995;36(9):1905-18.
X