Illuminating Cellular and Molecular Pathways of Atherosclerosis Regression
Atherosclerosis, the clogging of arteries by deposits of fat and cholesterol, is a major cause of cardiovascular disease. Decades of basic scientific and clinical research have significantly clarified the pathways that lead to the deposition of fat in arteries and to the growth of atheroma. Although reducing the rate of atherosclerosis progression is desirable and has been achieved clinically by lipid lowering medication, an ideal treatment for atherosclerosis-related cardiovascular disease is to promote its regression. Our laboratory's primary research focus is the investigation of the less well understood and studied biology of atherosclerosis regression.
