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Lovett DH, Mahimkar R, Raffai RL, Cape L, Zhu BQ, Jin ZQ, Baker AJ, Karliner JS
N-terminal truncated intracellular matrix metalloproteinase-2 induces cardiomyocyte hypertrophy, inflammation and systolic heart failure.
PloS one, 2013-07-16.
Eberlé D, Luk FS, Kim RY, Olivas VR, Kumar N, Posada JM, Li K, Gaudreault N, Rapp JH, Raffai RL
Inducible ApoE gene repair in hypomorphic ApoE mice deficient in the low-density lipoprotein receptor promotes atheroma stabilization with a human-like lipoprotein profile.
Arteriosclerosis, thrombosis, and vascular biology, 2013-06-20.
Raffai RL
Apolipoprotein E regulation of myeloid cell plasticity in atherosclerosis.
Current opinion in lipidology, 2012-10-01.
Raffai RL
Apolipoprotein E regulation of myeloid cell plasticity in atherosclerosis.
Current opinion in lipidology, Oct-2012;23(5):471-8.
View Abstract | PubMed AbstractPlus 
Gaudreault N, Kumar N, Olivas VR, Eberlé D, Rapp JH, Raffai RL
Macrophage-specific apoE gene repair reduces diet-induced hyperlipidemia and atherosclerosis in hypomorphic Apoe mice.
PloS one, 2012-05-14.
Lovett DH, Mahimkar R, Raffai RL, Cape L, Maklashina E, Cecchini G, Karliner JS
A novel intracellular isoform of matrix metalloproteinase-2 induced by oxidative stress activates innate immunity.
PloS one, 2012-04-03.
Eberlé D, Kim RY, Luk FS, de Mochel NS, Gaudreault N, Olivas VR, Kumar N, Posada JM, Birkeland AC, Rapp JH, Raffai RL
Apolipoprotein E4 domain interaction accelerates diet-induced atherosclerosis in hypomorphic Arg-61 apoe mice.
Arteriosclerosis, thrombosis, and vascular biology, 2012-03-22.
Gaudreault N, Kumar N, Olivas VR, Eberlé D, Rapp JH, Raffai RL
Macrophage-specific apoE gene repair reduces diet-induced hyperlipidemia and atherosclerosis in hypomorphic Apoe mice.
PloS one, 2012;7(5):e35816.
View Abstract | PubMed AbstractPlus 
Gaudreault N, Kumar N, Posada JM, Stephens KB, Reyes de Mochel NS, Eberlé D, Olivas VR, Kim RY, Harms MJ, Johnson S, Messina LM, Rapp JH, Raffai RL
ApoE suppresses atherosclerosis by reducing lipid accumulation in circulating monocytes and the expression of inflammatory molecules on monocytes and vascular endothelium.
Arteriosclerosis, thrombosis, and vascular biology, 2011-11-03.
Tie G, Yan J, Yang Y, Park BD, Messina JA, Raffai RL, Nowicki PT, Messina LM
Oxidized low-density lipoprotein induces apoptosis in endothelial progenitor cells by inactivating the phosphoinositide 3-kinase/Akt pathway.
Journal of vascular research, 2010-04-30.
Tao R, Hoover HE, Honbo N, Kalinowski M, Alano CC, Karliner JS, Raffai R
High-density lipoprotein determines adult mouse cardiomyocyte fate after hypoxia-reoxygenation through lipoprotein-associated sphingosine 1-phosphate.
American journal of physiology. Heart and circulatory physiology, 2010-01-08.
Tie G, Yan J, Yang Y, Park BD, Messina JA, Raffai RL, Nowicki PT, Messina LM
Oxidized low-density lipoprotein induces apoptosis in endothelial progenitor cells by inactivating the phosphoinositide 3-kinase/Akt pathway.
Journal of vascular research, 2010;47(6):519-30.  Epub 2010 Apr 30.
View Abstract | PubMed AbstractPlus 
Carpenter B, Lin Y, Stoll S, Raffai RL, McCuskey R, Wang R
VEGF is crucial for the hepatic vascular development required for lipoprotein uptake.
Development (Cambridge, England), 2005-06-08.
Zhang S, Picard MH, Vasile E, Zhu Y, Raffai RL, Weisgraber KH, Krieger M
Diet-induced occlusive coronary atherosclerosis, myocardial infarction, cardiac dysfunction, and premature death in scavenger receptor class B type I-deficient, hypomorphic apolipoprotein ER61 mice.
Circulation, 2005-06-20.
Raffai RL, Loeb SM, Weisgraber KH
Apolipoprotein E promotes the regression of atherosclerosis independently of lowering plasma cholesterol levels.
Arteriosclerosis, thrombosis, and vascular biology, 2004-12-09.
Raffaï RL, McPherson R, Weisgraber KH, Innerarity TL, Rassart E, Bersot TP, Milne RW
Antibody phenotyping test for the human apolipoprotein E2 isoform.
Clinical chemistry, Sep-2003;49(9):1524-6.
Raffaï RL, McPherson R, Weisgraber KH, Innerarity TL, Rassart E, Bersot TP, Milne RW
Antibody phenotyping test for the human apolipoprotein E2 isoform.
Clinical chemistry, 2003-09-01.
Raffai RL, Weisgraber KH
Cholesterol: from heart attacks to Alzheimer's disease.
Journal of lipid research, 2003-07-01.
Raffaï RL, Hasty AH, Wang Y, Mettler SE, Sanan DA, Linton MF, Fazio S, Weisgraber KH
Hepatocyte-derived ApoE is more effective than non-hepatocyte-derived ApoE in remnant lipoprotein clearance.
The Journal of biological chemistry, 2003-01-27.
R. Raffai,S. Loeb,K. Weisgraber
3P-0878 A mouse model to study the role of ApoE in atherosclerosis regression and plaque vulnerability in peripheral arterial disease.
Atherosclerosis Supplements, 2003-01-01.
Raffai RL, Weisgraber KH
Hypomorphic apolipoprotein E mice: a new model of conditional gene repair to examine apolipoprotein E-mediated metabolism.
The Journal of biological chemistry, 2002-01-15.
Raffaï RL
Periplasmic expression and purification of recombinant Fabs.
Methods in molecular biology (Clifton, N.J.), 2002-01-01.
Raffai RL, Dong LM, Farese RV, Weisgraber KH
Introduction of human apolipoprotein E4 "domain interaction" into mouse apolipoprotein E.
Proceedings of the National Academy of Sciences of the United States of America, 2001-09-11.
Libeu CP, Lund-Katz S, Phillips MC, Wehrli S, Hernáiz MJ, Capila I, Linhardt RJ, Raffaï RL, Newhouse YM, Zhou F, Weisgraber KH
New insights into the heparan sulfate proteoglycan-binding activity of apolipoprotein E.
The Journal of biological chemistry, 2001-08-10.
Raffaï R, Weisgraber KH, MacKenzie R, Rupp B, Rassart E, Hirama T, Innerarity TL, Milne R
Binding of an antibody mimetic of the human low density lipoprotein receptor to apolipoprotein E is governed through electrostatic forces. Studies using site-directed mutagenesis and molecular modeling.
The Journal of biological chemistry, 2000-03-10.
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